KMID : 0615720140310040029
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Jouranl of Korean Acupuncture and Moxibustion society 2014 Volume.31 No. 4 p.29 ~ p.32
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The Effects of Sterilization on Jakyakgamcho Decoction(Shaoyaogancao Decoction) Pharmacopuncture: an Investigation to Minimize Loss of Principal Components
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Lee Chong-Hwan
Jun Jae-Yun Lim Su-Jin Kim Hae-Sol Kim Ho-Sun Bae Young-Hyeon Lee In-Hee Kim Min-Jeong Kim Eun-Ji Ha In-Hyuk Lee Jin-Ho Lee Jae-Woong
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Abstract
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Objectives: Jakyakgamcho decoction is a traditional prescription known to be an effective pain control medication and muscle relaxant. For more localized treatment outcomes achieved in a shorter period of time, Jakyakgamcho decoction was reprocessed into a form of pharmacopuncture. An analysis of Jakyakgamcho decoction pharmacopuncture showed that there was a significant loss of paeoniflorin(Jakyak¡¯s index component). This study was designed to investigate ways to minimize this loss.
Methods: After making changes to the processing methods of Jakyakgamcho decoction pharmacopuncture, we measured the quantity of paeoniflorin using high performance liquid chromatography(HPLC) for a before-and-after analysis
Results: Paeoniflorin loss was observed 15 minutes after sterilization with Na2HPO4 at 121 ¡ÆC
Conclusions: It was found that paeoniflorin loss did not occur when pH was not controlled for during processing.
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KEYWORD
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Jakyak, Gamcho, Jakyakgamcho decoction pharmacopuncture, Paeoniflorin.
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