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KMID : 0615720140310040029
Jouranl of Korean Acupuncture and Moxibustion society
2014 Volume.31 No. 4 p.29 ~ p.32
The Effects of Sterilization on Jakyakgamcho Decoction(Shaoyaogancao Decoction) Pharmacopuncture: an Investigation to Minimize Loss of Principal Components
Lee Chong-Hwan

Jun Jae-Yun
Lim Su-Jin
Kim Hae-Sol
Kim Ho-Sun
Bae Young-Hyeon
Lee In-Hee
Kim Min-Jeong
Kim Eun-Ji
Ha In-Hyuk
Lee Jin-Ho
Lee Jae-Woong
Abstract
Objectives: Jakyakgamcho decoction is a traditional prescription known to be an effective pain control medication and muscle relaxant. For more localized treatment outcomes achieved in a shorter period of time, Jakyakgamcho decoction was reprocessed into a form of pharmacopuncture. An analysis of Jakyakgamcho decoction pharmacopuncture showed that there was a significant loss of paeoniflorin(Jakyak¡¯s index component). This study was designed to investigate ways to minimize this loss.

Methods: After making changes to the processing methods of Jakyakgamcho decoction pharmacopuncture, we measured the quantity of paeoniflorin using high performance liquid chromatography(HPLC) for a before-and-after analysis

Results: Paeoniflorin loss was observed 15 minutes after sterilization with Na2HPO4 at 121 ¡ÆC

Conclusions: It was found that paeoniflorin loss did not occur when pH was not controlled for during processing.
KEYWORD
Jakyak, Gamcho, Jakyakgamcho decoction pharmacopuncture, Paeoniflorin.
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